In this whitepaper, Professor Jian Wu, who is based at Fudan University Shanghai Medical College in China, and colleagues have established a murine NASH model which presents with significant steatohepatitis, inflammation, insulin resistance, and fibrotic progression in a scalable fashion. It is hoped this research may help researchers address the current challenges in this field and estimate the efficacy of pharmacotherapeutic candidates.
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Murine NASH model could provide insights into NASH development and progression