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Whitepaper

How CRISPR-based functional genomics is transforming drug discovery

A key challenge in disease research is the ability to assign functional characteristics from genomic sequences. With functional genomics you can gain valuable insights into the relationships between genotypes and phenotypes using large-scale data from genome-wide omics-based experiments.

Here, we discuss how CRISPR-based technologies and functional genomic screening are being applied to the field of drug discovery across multiple stages of the pipeline, from target identification to patient stratification and mechanism of action studies.

Learn more about:

  • Moving from RNAi to CRISPR screens
  • Improving target identification
  • Understanding drug response mechanisms
  • Moving from in vitro to in vivo

For research use only. Not for use in diagnostic procedures.

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How CRISPR-based functional genomics is transforming drug discovery

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