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Application Note

High throughput platforms to characterize a bispecific antibody subjected to force degradation

Forced degradation studies are critical in therapeutic antibody research, helping to evaluate stability across the product lifecycle. Common degradation pathways include aggregation, deamidation, oxidation, and fragmentation, with thermal stress being a frequently studied factor.

This application note explores the stability of a bispecific antibody targeting mouse CD200 and CD47 under thermal stress, using a high-throughput, no-wash HTRF™ assay to assess its binding activity.

Read this application note to learn more.

For research use only. Not for use in diagnostic procedures.

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High throughput platforms to characterize a bispecific antibody subjected to force degradation

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