This literature review illustrates the possibilities of GPCR monitoring with HTRF second messenger cAMP and IP-1 assays in a cardiovascular context. It features experiments and data from published studies that investigated b-arrestin-biased ligands of the angiotensin II and apelin receptors, as well as inhibitor screening of the relaxin receptor and atrial natriuretic peptide signaling through ANPRs.
Features
For research use only. Not for use in diagnostic procedures.
GPCR signaling in cardiovascular research addressed with HTRF second messenger assays