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Application Note

FOXO1 in Non-Alcoholic Fatty Liver Disease

HTRF™ application note

Non-alcoholic fatty liver disease (NAFLD) includes a range of liver conditions unrelated to alcohol consumption that results in inflammation and fibrosis. NAFLD may progress to non-alcoholic steatohepatitis (NASH), cirrhosis, or liver failure; and is closely linked to metabolic syndromes through activation of glucose and lipogenesis-regulating transcription factors, such as FOXO1.

Download this complimentary application note to explore the use of an HTRF assay for the evaluation of FOXO1 in a fatty liver disease model and evaluate:

  • Pro-inflammatory cytokine activation
  • The benefits of HTRF assays compared to western blot
  • A model system for fatty liver disease and insulin resistance

For research use only. Not for use in diagnostic procedures.

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FOXO1 in Non-Alcoholic Fatty Liver Disease

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