Read this application note to learn how a dual screen using CRISPRi and CRISPRa gene modulation technologies in parallel allows for the identification of drug-gene interactions through paired gene perturbation analysis.
This combination approach offers researchers a novel, powerful and systematic way to explore drug mechanisms of action, identify novel bio-markers and provides compelling targets of use for the development of combination therapies.
For research use only. Not for use in diagnostic procedures.
The dual screen: Parallel genome-wide CRISPRi and CRISPRa screening