CRISPR screening provides a powerful approach to quickly identify the genetic interactions that underlie a treatment response.
In this application note, we demonstrate that by probing the transcriptome of each individual cell for its response to a treatment or a stimulus, we can link gene expression signature with drug response. This supports the detection of biomarkers and the development of personalized medicines.
For research use only. Not for use in diagnostic procedures.
CRISPRsc: Pooled CRISPR screening with single-cell transcriptome resolution