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Automated-DNA-purification-from-FFPE-samples-for-NGS-library-preparation
Application Note

Automated library preparation with Covaris ultrasonificator

Next-generation sequencing (NGS) has revolutionized the field of genomic research. The dropping costs and technology improvements have made feasible the application of NGS to high-throughput studies, providing a new and powerful tool to scientists working in fields as diverse as plant biology and human genetics. A crucial step in the NGS workflow is the preparation of the library for sequencing. A poor-quality library can lead to profound technical artifacts that might influence the results and, ultimately, data interpretation. The isolation of pure high molecular weight DNA or full-length RNA and a consistent and robust fragmentation protocol are the foundations to successful library preparation. To ensure that both conditions are met, chemagen has integrated the Covaris® Focused-ultrasonicator to its nucleic acid purification workflow. By exploiting the chemagic™ technology, ensures optimal extraction of DNA and RNA from a wide range of sample types. The purified nucleic acid is then fragmented using the Covaris® Focused-ultrasonicator. The integration of the Covaris® system with the chemagic™ workflows ensures unparalleled high-throughput capabilities from primary sample to DNA and RNA fragments of the desired size ready for library preparation.

For research use only. Not for use in diagnostic procedures.

Revvity is a trademark of Revvity, Inc. All other trademarks are the property of their respective owners.

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Automated library preparation with Covaris ultrasonificator

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