Offering
Solid experience with custom labeling
Solid experience with custom labeling
Our offering includes:
- Labeling of small molecules with Europium & Terbium cryptates:
- Aromatics & heterocycle compounds
- Steroids
- Saccharides
- Nucleosides
- Derivatization of pharmacophore
- Introduction of linkers prior to labeling, to retain activity
- Reproduction of a synthesis described in the literature
Process
A clear and straightforward process
A clear and straightforward process
Deliverables include:
- To supply a compound with high purity level
- To package exact quantities based on UV quantification
- To determine a process to solubilize the conjugated molecule
- To supply safety documents (MSDS files)
- To supply an Analysis certificate including HPLC / UPLC traces, UV and MS spectra.
- To supply HRMS analysis on request
- Access to NMR facilities to confirm structures (if scale and type of molecule are compatible with such analysis)
- Vial label with solvent- and temperature-resistant inks
Next-generation facilities
The chemistry labs are equipped with the latest technology and equipment, ready to deliver the best possible synthetic chemistry service and the most precise analytical reporting.
Equipment includes:
- Several fume hoods
- Rotating evaporators under fume hoods, ensuring a healthy laboratory atmosphere
- UPLC MS for reaction monitoring
- Semi preparative HPLC (purification of small quantities)
- Preparative HPLC (up to 100 mg)
- Automatized chromatography purification (Reveleris)
- Large set of HPLC columns
- Speed vac for solvent removal
- Lyophilizer
- Microwave reactor (CEM) to speed up reactions and reduce side reactions
- Mass spectrometer (simple quadripole) coupled to UPLC in a safe room away from solvent
- Large number of chemical reagents stored in safe room site
- Reaction under inert atmosphere (argon line)
- Reaction at low temperature
- Hydrogenation reactor facilities
- Reaction under pressure with steel reactor
- UV spectrometer