NEW pHSense™ reagents for internalization studies
Discover a powerful new plate reader tool specifically designed for cell surface target internalization studies necessary for ADC and GPCR research.
Discover a powerful new plate reader tool specifically designed for cell surface target internalization studies necessary for ADC and GPCR research.
pHSense probes are plate reader-compatible reagents with time-resolved fluorescence (TRF) readout specifically developed for internalization studies. This technology reinforces Revvity's commitment to advancing drug discovery workflows. pHSense offers:
- Higher throughput plate-based pH sensitive internalization reagents
- Superior signal-to-background for more reliable pharmacological data
- Versatility across suspension & adherent cells
Most recently released targets
In the race to the next big breakthrough, you need to have the best tools available. We are constantly working to keep pace with the speed of your innovation to provide you with the products you need.
In the race to the next big breakthrough, you need to have the best tools available. We are constantly working to keep pace with the speed of your innovation to provide you with the products you need.
New assays are available in AlphaLISA™ SureFire® Ultra™, AlphaLISA™, and HTRF™ technologies within several different therapeutic areas and research fields.
- Inflammation: Caspase-3 Cleaved Asp175, Caspase-3 Total, IRF7 Phospho-S477 and Total, NF-κB p65 Biotin Free Phospho-S536 and Biotin Free Total, STING Phospho-S366, TNFAIP3 Total
- Metabolic: CHOP Total, Glucagon GIPR
- Neuroscience: CHOP Total, CSF1R Phospho-Y561, Phospho-Y699, Phospho-Y708, Phospho-Y723 and Total, HSP70 1A/1B Total, HTT Aggregation, Mutant, and Total, PKR Phospho-T446, RAB12 Total, Tau Aggregate
- Oncology: ARID1A Total, B-Raf Phospho-S446 and Total, Caspase-3 Cleaved Asp175, Caspase-3 Total, CHOP Total, CSF1R Phospho-Y561, Phospho-Y699, Phospho-Y708, Phospho-Y723 and Total, DDR1 Phospho-Y796 and Total, HSP70 1A/1B Total, IRF7 Phospho-S477 and Total, NF-κB p65 Biotin Free Phospho-S536 and Biotin Free Total, PDGFRα Phospho-Y720 and Total, PKR Phospho-T446, RAB12 Total, SKP2 Total, TNFAIP3 Total, WDR5 Total
- Virology: PKR Phospho-T446, STING Phospho-S366
Newest target videos
Discover brief animated videos providing information on specific targets and research areas that are addressed by our newly released assay kits!
Discover brief animated videos providing information on specific targets and research areas that are addressed by our newly released assay kits!
LRRK2 in Parkinson's disease
Key protein targets in TPD
Aurora kinases in the cell cycle
The power of cytokines
Autophagy and its potential in therapeutics
HTT in Huntington’s disease pathology
AAVs as gene therapy vectors
Exploring Janus kinases
BRD proteins as therapeutic targets
LC3B: Key marker of autophagy
Targeting the ECM
Synthetic lethality in cancer
Explore Alpha, HTRF, LANCE Ultra, and DELFIA assay technologies
Our Alpha, HTRF™, LANCE™ Ultra™ TR-FRET, and DELFIA™ TRF technologies offer alternatives to standard ELISA assay kits, each with a larger dynamic range and higher signal-to-noise ratio. Alpha, HTRF and LANCE Ultra TR-FRET have the added advantage of having no wash or separation steps, saving you valuable time. Discover sandwich assays, protein detection assays, cell based assays, and more!
Our Alpha, HTRF™, LANCE™ Ultra™ TR-FRET, and DELFIA™ TRF technologies offer alternatives to standard ELISA assay kits, each with a larger dynamic range and higher signal-to-noise ratio. Alpha, HTRF and LANCE Ultra TR-FRET have the added advantage of having no wash or separation steps, saving you valuable time. Discover sandwich assays, protein detection assays, cell based assays, and more!
Alpha is a bead-based, no-wash luminescent technology. When Alpha Donor and Acceptor beads are brought together through binding to the target, a cascade of chemical reactions is set in motion, creating an amplified signal. These versatile beads are conjugated with various biomolecules that enable the detection of unique biological events, offering maximum flexibility.
HTRF (Homogeneous Time Resolved Technology) is a FRET-based, no-wash technology. HTRF technology is rapid, homogeneous, easy to use and to automate, allows extreme miniaturization and easy assay development. HTRF technology can be used in competitive and noncompetitive formats, performed as cellular or biochemical assays, and thus can been applied to a variety of applications.
LANCE (Lanthanide Chelate Excite) Ultra TR-FRET is a no wash proximity assay that combines the benefits of time resolution (TR) with fluorescence resonance energy transfer (FRET) principles by using energy donor and energy acceptor fluorophore labels.
DELFIA (dissociation-enhanced lanthanide fluorescence immunoassay) is a time-resolved fluorescence (TRF) intensity technology. DELFIA has a similar assay principle and workflow to that of a traditional ELISA, but with the added benefits of a stable, time-resolved fluorescent signal improving assay dynamic range. DELFIA also offers a multiplexing capability.
