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M-PVA Magnetic Beads

Develop your own assay with robust family of chemagic™ M-PVA magnetic beads enhanced by a vast range of functionalities

Our M-PVA magnetic beads are small iron oxide particles encapsulated in a matrix of polyvinyl alcohol. Their functional group defines their binding affinity to either nucleic acids, proteins or biomolecular molecules. These paramagnetic beads are designed to exhibit strong magnetic properties, allowing them to be manipulated using an external magnetic field. Thus, they are ideal for extraction of target molecules from a complex mixture. Applications of magnetic beads span various fields, including biology, chemistry, medicine, and materials science.

  • DNA/RNA binding with carboxylated magnetic beads
  • Magnetic Streptavidin beads for biotinylated targets
  • M-PVA Magnetic Oligo dT Beads for mRNA binding
  • Protein binding with NHS activated magnetic beads
  • Size selection bead solution for NGS reaction clean up
  • IVT reaction clean up beads


For research use only. Not for use in diagnostic procedures.
 

M-PVA Magnetic Beads

Size selection beads

This method of size directed nucleic acid extraction is commonly known as SPRI (Solid Phase Reversible Immobilization). Revvity’s size selection beads are designed for rapid manual and automated clean up and size selection of DNA and RNA fragments from a variety of reaction mixtures, used in NGS library preparations.

Clean-up of RNA and DNA with typical recovery yields for DNA ≥ 80 %, and for RNA between 70–100%.

Size Selection: The typical sample amount of double stranded DNA fragments is 5 ng to 1 µg. By using the tunable size selection method DNA fragment libraries with a size range of 150 bp to 800 bp can be produced. All components can be kept and processed completely at room temperature.

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This method of size directed nucleic acid extraction is commonly known as SPRI (Solid Phase Reversible Immobilization). Revvity’s size selection beads are designed for rapid manual and automated clean up and size selection of DNA and RNA fragments from a variety of reaction mixtures, used in NGS library preparations.

Clean-up of RNA and DNA with typical recovery yields for DNA ≥ 80 %, and for RNA between 70–100%.

Size Selection: The typical sample amount of double stranded DNA fragments is 5 ng to 1 µg. By using the tunable size selection method DNA fragment libraries with a size range of 150 bp to 800 bp can be produced. All components can be kept and processed completely at room temperature.

Suggested products

IVT reaction clean-up kit

The IVT reaction clean-up kit enables fast and simple purification and concentration of up to 500 µg of RNA from in vitro transcription (IVT) and other enzymatic reactions.

  • Ideal for purification of synthesized RNA following high-yield in vitro transcription reactions
  • Optimized for the clean-up of RNA after enzymatic treatments including DNase I, Proteinase K, labeling and capping
  • Efficiently purify RNA ≥ 25 nt (a simple modification enables purification of RNA ≥ 15 nt) 
  • Elute in ≥ 50 µl for concentrated RNA with 70-100% RNA recovery
  • Purified RNA is ready for use in a wide variety of downstream applications, including microinjection and transfection.
  • All components can be kept and processed completely at room temperature.

The IVT reaction clean-up kit enables fast and simple purification and concentration of up to 500 µg of RNA from in vitro transcription (IVT) and other enzymatic reactions.

  • Ideal for purification of synthesized RNA following high-yield in vitro transcription reactions
  • Optimized for the clean-up of RNA after enzymatic treatments including DNase I, Proteinase K, labeling and capping
  • Efficiently purify RNA ≥ 25 nt (a simple modification enables purification of RNA ≥ 15 nt) 
  • Elute in ≥ 50 µl for concentrated RNA with 70-100% RNA recovery
  • Purified RNA is ready for use in a wide variety of downstream applications, including microinjection and transfection.
  • All components can be kept and processed completely at room temperature.