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Automated rotor-stator homogenizers and workstations

Labs across all industries consistently aim to improve their workflows, especially as they scale up their sample throughput and consider leveraging automation where appropriate.

After samples arrive at research labs, they tend to be processed immediately or reformatted for safe storage until time of downstream genomic and proteomic assessment. Using semi-automated or automated, walkaway workstations, labs could potentially address major bottlenecks in their sample prep. We offer solutions that enable streamlined biobanking and biorepository workflows.

Within the solutions we offer for operational efficiency, automation-assisted sample prep can help labs improve their turn-around-time and facilitates maximal use of both employee and equipment resources. Within sample prep, upfront sample homogenizations of tissues, complex matrices, and cells prior to molecular analysis of proteins, nucleic acids, lipids, and other common biological analytes can be a challenge due to the sheer variability that can exist in a biological sample. With automation, however, there can be consistency in both workflow and technical specifications of sample homogenization that is hard to attain with manual methods. Our Omni Prep multi-sample homogenizer, Prep 96 automated homogenizer, and LH96 automated homogenizer workstation are rotor-stator homogenizers that enable a range of sample throughput , whether just starting out with automated homogenization or looking to increase their current mid-throughput capacity. Be confident automating your workflows and scaling your throughput with Revvity.

We also offer a comprehensive list of accessories and recommended bulk tubes for automation.


For research use only. Not for use in diagnostic procedures.

Automated Homogenizers
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Omni Prep96 automated homogenizer

The Omni Prep 96 automated homogenizer enables walk-away processing of up to 96 samples in a single batch, in tube sizes ranging from 2 to 50 mL. The Omni Prep 96 workflow software permits user-friendly method development and deployment via an interactive GUI, which supports human-like vertical and horizontal motions for probe movement within a sample tube. Using our whisper drive technology™, the unit is virtually maintenance-free and ultra-quiet with 4 x 100-watt brushless motors that can hold processing speeds to ± 1% accuracy. The unit is also compatible with our Omni Tip™ plastic generator probes for labs looking for disposable solutions to minimize cross-contamination risk.

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The Omni Prep 96 automated homogenizer enables walk-away processing of up to 96 samples in a single batch, in tube sizes ranging from 2 to 50 mL. The Omni Prep 96 workflow software permits user-friendly method development and deployment via an interactive GUI, which supports human-like vertical and horizontal motions for probe movement within a sample tube. Using our whisper drive technology™, the unit is virtually maintenance-free and ultra-quiet with 4 x 100-watt brushless motors that can hold processing speeds to ± 1% accuracy. The unit is also compatible with our Omni Tip™ plastic generator probes for labs looking for disposable solutions to minimize cross-contamination risk.

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Omni Prep multi-sample homogenizer

The Omni Prep multi-sample homogenizer supports simultaneous processing of up to size samples, in tube ranging from 1.5 mL to 50 mL. The sample rack oscillates to mimic the movements of manual homogenization through the entire tube volume, and the whisper drive technology enables a virtually maintenance-free and ultra-quiet experience during operations. The 150 watt brushless motor holds processing speeds to ± 1% accuracy, and the unit is compatible with the Omni Tip plastic generator probes for labs looking for a one-time use, disposable solution to significantly minimize risk of cross-contamination.

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The Omni Prep multi-sample homogenizer supports simultaneous processing of up to size samples, in tube ranging from 1.5 mL to 50 mL. The sample rack oscillates to mimic the movements of manual homogenization through the entire tube volume, and the whisper drive technology enables a virtually maintenance-free and ultra-quiet experience during operations. The 150 watt brushless motor holds processing speeds to ± 1% accuracy, and the unit is compatible with the Omni Tip plastic generator probes for labs looking for a one-time use, disposable solution to significantly minimize risk of cross-contamination.

Learn more

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Omni LH 96 automated homogenizer workstation

The Omni LH 96 automated homogenizer workstation (LH96) boasts a small footprint that saves valuable bench space and the whisper drive technology that ensures a virtually maintenance-free and ultra-quiet operation using 8 x 40 watt brushless motors, which holds processing speeds to ± 1% accuracy. This workstation automates not only homogenization, but also accompanying liquid handling, pipetting, liquid transfer, weighing, diluting, and sample transfer using an intuitive and interactive GUI. Compatible with the Omni Tip plastic generator probes for disposal after one-time use or the hybrid and stainless-steel generator probes that can be subjected to a cleaning cycle via the ultrasonic bath for reuse within the automated workflow.

The Omni LH 96 automated homogenizer workstation (LH96) boasts a small footprint that saves valuable bench space and the whisper drive technology that ensures a virtually maintenance-free and ultra-quiet operation using 8 x 40 watt brushless motors, which holds processing speeds to ± 1% accuracy. This workstation automates not only homogenization, but also accompanying liquid handling, pipetting, liquid transfer, weighing, diluting, and sample transfer using an intuitive and interactive GUI. Compatible with the Omni Tip plastic generator probes for disposal after one-time use or the hybrid and stainless-steel generator probes that can be subjected to a cleaning cycle via the ultrasonic bath for reuse within the automated workflow.

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Omni Prep Homogenizer

6 Sample Automated Homogenizer The innovative Omni Prep Multi-Sample Homogenizer supports simultaneous homogenization of up to six samples in a single process in sample tubes ranging from 1.5 mL to 50 mL. The Omni Prep microprocessor control allows the user to program both time and speed for processing up to 10 minutes at variable speeds up to 30,000 rpm. The oscillating sample rack mimics manual homogenization by transitioning the generator probes through the entire tube volume to ensure robust homogenization. Note: The Omni Prep is sold as a customizable homogenizing system. Requires at least one processing rack, three tube holders and six stainless steel generator probes or Omni Tips.

Part Number: 06-021
Omni Prep 96 Automated Homogenizer

The Prep 96 is a fully automated sample prep workstation. The design significantly reduces bottlenecks and increases throughput, enabling true walk-away processing in your lab. User-friendly programming makes saving, recalling, or changing existing protocols easy. Probe drive motors feature high-power brushless motors for maintenance-free, ultra quiet sample processing.

Part Number: 51-02A-1
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Application Note
Application Note
Automation of tissue homogenization in protein analysis workflows using the Omni LH96 automated workstation

Accurately quantifying proteins in biospecimens is critical to studies that positively impact our understanding of human health and disease. Within staple techniques, LC-MS has become a powerful analytical method that provides insights into project milestones, not limited to drug efficacy, mechanisms of action, target engagement, and safety. From mRNA and lipid nanoparticles (LNPs) to gene therapy (GTx) and protein degraders (PROTAC), LC-MS is making an impact across drug modalities and their discovery platforms. Tissues, whether for protein or other analytes investigation, are immensely valuable biospecimens that touch the success of multiple streams in disease research, where variability in sample handling and analyte preparation are core laboratory challenges. Many labs are turning to automated homogenizers to accelerate their tissue prep workflows. In this application note, valuable data is shared from Pfizer’s on-site evaluation and adoption of the Omni automated homogenizer: Benchmark and efficiency testing on several tissue types Comparison data to semi-automated bead milling Increase in sample size/weight processing range Reduction in overall processing time, hands-on analyst time, and ease of knowledge transfer/technology training For research use only. Not for use in diagnostic procedures.

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Genomics and epigenomics with automated sample prep workflows

Genomics and Epigenomics research sample prep automation workflow flyer

Application Note
Application Note
High-throughput extraction of cannabinoids from cannabis analog on the Omni Prep 96 automated homogenizer

Cannabinoid quantification is a crucial process in cannabis production and testing, where the quantity of abundant cannabinoids such as THC, CBD, and others are assessed. The most common method involves milling the flower or edibles into homogenous mixtures using an organic solvent for extraction, followed by analysis via HPLC or mass spectrometry. This study evaluated the Omni Prep 96 automated homogenizer’s efficiency for cannabinoid extraction via walk-away rotor-stator technology from a spiked cannabis analog, fresh hops. Results were obtained for CBA and THC recovery rates of the spike standards and compared to recovery by manual mixing only. For research use only. Not for use in diagnostic procedures.

Product Note
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Omni Prep Multi-sample Homogenizer product marketing sheet

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Prep 96 Automated Homogenizer Brochure